Elisa Nusbaum 's blog ::Myth # 2: Lung Cancer is a Death Sentence
In a recent press release, researchers have announced that they have found a way to predict who will survive when an older woman has early stage lung cancer. This is a significant finding, and could impact the type of care and treatments that women receive when they have lung cancer. Every year lung cancer claims the lives of over 70,000 women, and 98,000 are diagnosed with lung cancer. Researchers at UCLA's Jonsson Comprehensive Cancer Center made the announcement that they have been able to determine how to predict who will survive when diagnosed with early stage lung cancer. Over 98,000 women are diagnosed with lung cancer every year. Women over 65 years old, who also had high aromatase levels, faced the highest risk of dying from lung cancer. This research study demonstrated a link between high levels of the enzyme aromatase, to these lower survival rates for women with Stage I or Stage II lung cancer. The enzyme, aromatase, uses androgens in our bodies to make the hormone estrogen. Aromatase plays a much larger role in lung cancers that affect women than men. Their discovery of a correlation between high levels of aromatase and low survival rates opens the door for the potential to develop a new tool that can predict a woman's probability of surviving lung cancer. Aromatase inhibitors are already being used in breast cancer treatment. It is expected that researchers will focus on developing therapy treatments using aromatase for lung cancer, too. "All indications suggest that this is a very powerful prognostic marker that lets us predict which patients have a higher likelihood of prolonged survival versus death from lung cancer. If doctors know that a woman has a higher probability of longer-term survival, they may choose a more strategic course of action compared to a woman with a more aggressive form of lung cancer, where doctors might choose a more aggressive course of therapy. Another notable finding from this study is that we're able to predict survival at a relatively early stage of the disease, when we have more treatment options," said Lee Goodglick, an associate professor in the Department of Pathology and Laboratory Medicine. Prior to this research study, scientists had known that estrogen had a role in lung cancer, but they did not know the extent or the reasons for its role. Scientists knew that animals that had either aromatase or estrogen also developed human lung cancer tumors. The fully study has been published in the November 1, 2007 issue of Cancer Research. Source: http://www.newswise.com/p/articles/view/534895/ |
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